Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 19/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 18/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 18/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7213212 | 0.99 | ADRA1A (0.51) | ADRA1AADRA1DADRA1BHRH1 | |
| Hydrochloric Acid SCHEMBL6967665 | 0.94 | ADRA1A (0.51) | ADRA1AADRA1DADRA1BHRH1 | |
| SCHEMBL7842061 | 0.78 | ADRA1A (0.66) | ADRA1AADRA1DADRA1BHRH1 | |
| Hydrochloric Acid SCHEMBL7226735 | 0.77 | ADRA1A (0.65) | ADRA1AADRA1DADRA1BHRH1 | |
| SCHEMBL7084868 | 0.77 | ADRA1A (0.57) | ADRA1AADRA1DADRA1BHRH1 | |
| SCHEMBL7216965 | 0.77 | ADRA1A (0.57) | ADRA1AADRA1DADRA1BHRH1 | |
| Hydrochloric Acid SCHEMBL8163246 | 0.74 | ADRA1D (0.66) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7080203 | 0.73 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BHRH1 | |
| Hydrochloric Acid SCHEMBL6962621 | 0.73 | ADRA1D (0.66) | ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL6969566 | 0.72 | ADRA1D (0.44) | ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988295-A4 | HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 2003-08-13 | — | — | EP | disclosed |
| EP-0988295-A1 | HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998057940-A1 | HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |