Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.64 |
| ▸ | DRD2 | P14416 | 6/20 | 0.61 |
| ▸ | DRD4 | P21917 | 5/20 | 0.61 |
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | RHOC | P08134 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224906 | 0.88 | NOTUM (0.68) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL8895360 | 0.85 | NOTUM (0.68) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL6961783 | 0.84 | DRD2 (0.58) | NOTUMDRD2DRD4XIAPTSHR | |
| SCHEMBL6960804 | 0.84 | TSHR (0.51) | NOTUMDRD2DRD4TSHRMEN1 | |
| SCHEMBL6960678 | 0.84 | DRD2 (0.58) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL6961286 | 0.82 | NOTUM (0.48) | NOTUMDRD2DRD4MEN1KMT2A | |
| SCHEMBL27447403 | 0.81 | TSHR (0.48) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL6962584 | 0.81 | BIRC2 (0.57) | NOTUMDRD2XIAPBIRC2TSHR | |
| SCHEMBL4637311 | 0.80 | TSHR (0.81) | NOTUMDRD2DRD4TSHRMEN1 | |
| SCHEMBL8901483 | 0.80 | NOTUM (0.65) | NOTUMDRD2DRD4XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807631-B1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 2003-03-12 | — | — | EP | disclosed |
| CN-1059904-C | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 2000-12-27 | — | — | CN | disclosed |
| US-5981752-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5773618-A | PYRROLOQUINOLINONE DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1998-06-30 | — | — | US | disclosed |
| CN-1172809-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 1998-02-11 | — | — | CN | disclosed |
| EP-0807631-A1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-11-19 | — | — | EP | disclosed |