Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127939 | 0.86 | MAPT (0.54) | TSHRBRD4ATAD2MAPTMEN1 | |
| SCHEMBL8613724 | 0.86 | MAPT (0.54) | TSHRBRD4ATAD2MAPTMEN1 | |
| SCHEMBL6966671 | 0.84 | NOTUM (0.64) | TSHRMAPTMEN1KMT2ANOTUM | |
| SCHEMBL6961783 | 0.83 | DRD2 (0.58) | TSHRMAPTMEN1KMT2ANOTUM | |
| SCHEMBL6960678 | 0.83 | DRD2 (0.58) | TSHRMAPTMEN1KMT2ANOTUM | |
| SCHEMBL27559025 | 0.82 | BRD4 (0.55) | TSHRBRD4ATAD2MAPTMEN1 | |
| SCHEMBL27447403 | 0.80 | TSHR (0.48) | TSHRMAPTMEN1KMT2ANOTUM | |
| SCHEMBL6962584 | 0.80 | BIRC2 (0.57) | TSHRMAPTMEN1KMT2ANOTUM | |
| SCHEMBL4637311 | 0.79 | TSHR (0.81) | TSHRMAPTMEN1KMT2ANOTUM | |
| SCHEMBL21712183 | 0.79 | ALDH1A1 (0.49) | TSHRBRD4ATAD2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807631-B1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 2003-03-12 | — | — | EP | disclosed |
| CN-1059904-C | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 2000-12-27 | — | — | CN | disclosed |
| US-5981752-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5773618-A | PYRROLOQUINOLINONE DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1998-06-30 | — | — | US | disclosed |
| CN-1172809-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 1998-02-11 | — | — | CN | disclosed |
| EP-0807631-A1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-11-19 | — | — | EP | disclosed |