Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205538 | 1.00 | PIN1 (0.53) | PIN1CASP3MDM2KMT2AMDM4 | |
| SCHEMBL5207070 | 1.00 | PIN1 (0.53) | PIN1CASP3MDM2KMT2AMDM4 | |
| SCHEMBL5205826 | 0.90 | PIN1 (0.54) | PIN1CASP3MDM2KMT2AMDM4 | |
| SCHEMBL6970042 | 0.89 | PIN1 (0.53) | PIN1CASP3MDM2KMT2AMDM4 | |
| SCHEMBL5206190 | 0.89 | PIN1 (0.53) | PIN1CASP3MDM2KMT2AMDM4 | |
| SCHEMBL5202706 | 0.89 | PIN1 (0.53) | PIN1CASP3MDM2KMT2AMDM4 | |
| SCHEMBL5207276 | 0.86 | PIN1 (0.46) | PIN1CASP3MDM2 | |
| SCHEMBL5204072 | 0.86 | PIN1 (0.46) | PIN1CASP3MDM2 | |
| SCHEMBL5207064 | 0.82 | CYP3A4 (0.37) | PIN1CASP3KMT2ACFD | |
| SCHEMBL6966683 | 0.82 | CYP3A4 (0.37) | PIN1CASP3KMT2ACFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333025-A1 | CYANOPYRROLIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2003-08-06 | — | — | EP | disclosed |