Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062968 | 0.83 | — | — | |
| SCHEMBL18068301 | 0.82 | AR (0.31) | ACEKMT2ACCNCCDK8 | |
| SCHEMBL18068300 | 0.82 | AR (0.31) | ACEKMT2ACCNCCDK8 | |
| SCHEMBL2031105 | 0.82 | CCNC (0.33) | ACECCNCCDK8 | |
| SCHEMBL11697415 | 0.82 | AR (0.31) | ACEKMT2ACCNCCDK8 | |
| SCHEMBL28030824 | 0.80 | CCNC (0.33) | CCNCCDK8 | |
| SCHEMBL6599014 | 0.80 | CCNC (0.30) | CCNCCDK8 | |
| SCHEMBL8085940 | 0.78 | ALDH1A1 (0.36) | MEN1KMT2A | |
| SCHEMBL9280738 | 0.78 | ACE (0.42) | BRD4ACEMEN1MAPTCYP2C9 | |
| SCHEMBL24629769 | 0.77 | KDM4E (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6350774-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2002-02-26 | — | — | US | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| US-5475020-A | Selective vasoconstrictors | GLAXO GROUP LIMITED (GB) | 1995-12-12 | — | — | US | disclosed |
| EP-0623128-A1 | INDOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014087-A1 | INDOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |