Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30365867 | 0.86 | ACE (0.43) | ACEBRD4KMT2AMEN1MAPT | |
| SCHEMBL7759537 | 0.82 | GBA1 (0.39) | ACESMN1; SMN2ALDH1A1 | |
| SCHEMBL6966874 | 0.78 | BRD4 (0.43) | ACEBRD4SMN1; SMN2LMNAKMT2A | |
| SCHEMBL15668633 | 0.75 | ACE (0.49) | ACEITGB3ITGA2B | |
| SCHEMBL16859438 | 0.74 | ACE (0.36) | ACESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL2442693 | 0.74 | CYP3A4 (0.50) | ACESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL2442696 | 0.74 | CYP3A4 (0.50) | ACESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL31291796 | 0.74 | CYP3A4 (0.50) | ACESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL21383815 | 0.74 | PIK3CD (0.56) | ACESMN1; SMN2LMNAALDH1A1PIK3CD | |
| SCHEMBL16430251 | 0.74 | HRH3 (0.49) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5458660-A | Fuel compositions | SHELL OIL COMPANY (US) | 1995-10-17 | — | — | US | disclosed |