Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 5/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956624 | 0.90 | NPY5R (0.58) | FAAHKCNH2KMT2AFLT3FLT1 | |
| SCHEMBL6961788 | 0.88 | FAAH (0.69) | FAAHKMT2AFLT3FLT1KDR | |
| SCHEMBL6955329 | 0.87 | FAAH (0.58) | FAAHKMT2AFLT3FLT1KDR | |
| SCHEMBL6954187 | 0.87 | FLT3 (0.55) | FAAHKCNH2FLT3FLT1KDR | |
| SCHEMBL6961253 | 0.86 | NPY5R (0.58) | FAAHKMT2AFLT3KDRALDH1A1 | |
| SCHEMBL6959291 | 0.85 | FAAH (0.66) | FAAHKMT2AFLT3FLT1KDR | |
| SCHEMBL6959800 | 0.85 | FAAH (0.58) | FAAHKMT2AFLT3FLT1KDR | |
| SCHEMBL6963922 | 0.85 | FAAH (0.58) | FAAHKMT2AFLT3FLT1KDR | |
| SCHEMBL6952931 | 0.84 | FAAH (0.55) | FAAHKMT2AFLT3FLT1KDR | |
| SCHEMBL6961328 | 0.83 | MAPT (0.56) | FAAHKCNH2KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | claimed |
| EP-0955293-A1 | NOVEL UREA DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-10 | — | — | EP | claimed |
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0955293-A1 | NOVEL UREA DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-10 | — | — | EP | disclosed |