Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956624 | 0.90 | NPY5R (0.58) | MAPTNPY5RALDH1A1KMT2ALMNA | |
| SCHEMBL6959277 | 0.89 | RBP4 (0.53) | MAPTNPY5RALDH1A1GAAKMT2A | |
| SCHEMBL6954187 | 0.87 | FLT3 (0.55) | NPY5RCHRNA3FAAHKCNH2CSNK2A2 | |
| SCHEMBL6962480 | 0.86 | NPY5R (0.63) | MAPTNPY5RTHRBLMNACHRNA3 | |
| SCHEMBL6963922 | 0.83 | FAAH (0.58) | MAPTNPY5RALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6968019 | 0.83 | NPY5R (0.67) | MAPTNPY5RKMT2ASMN1; SMN2FAAH | |
| SCHEMBL6966880 | 0.83 | FAAH (0.55) | MAPTNPY5RALDH1A1GAAKMT2A | |
| SCHEMBL13234933 | 0.81 | MAPT (0.76) | MAPTALDH1A1GAAKMT2ATHRB | |
| SCHEMBL6965780 | 0.80 | MAPT (0.55) | MAPTNPY5RALDH1A1GAAKMT2A | |
| SCHEMBL6963875 | 0.80 | NPY5R (0.59) | MAPTNPY5RKMT2AFAAHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | claimed |
| EP-0955293-A1 | NOVEL UREA DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-10 | — | — | EP | claimed |
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0955293-A1 | NOVEL UREA DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-10 | — | — | EP | disclosed |