Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15624412 | 0.76 | TRPV1 (0.47) | EPHX2TRPV1 | |
| SCHEMBL31009386 | 0.74 | EPHX2 (0.44) | EPHX2ALDH1A1MAPTATMHSD11B1 | |
| SCHEMBL31608519 | 0.74 | EPHX2 (0.44) | EPHX2ALDH1A1MAPTATMHSD11B1 | |
| SCHEMBL8436654 | 0.74 | EPHX2 (0.44) | EPHX2ALDH1A1MAPTATMHSD11B1 | |
| SCHEMBL610024 | 0.74 | EPHX2 (0.44) | EPHX2ALDH1A1MAPTATMHSD11B1 | |
| SCHEMBL2305693 | 0.73 | EPHX2 (0.43) | EPHX2HSD11B1NFE2L2MEN1KMT2A | |
| SCHEMBL162911 | 0.73 | EPHX2 (0.43) | EPHX2HSD11B1NFE2L2MEN1KMT2A | |
| SCHEMBL120643 | 0.73 | RPS6KA5 (0.45) | EPHX2HSD11B1NFE2L2MEN1KMT2A | |
| SCHEMBL12153212 | 0.73 | EPHX2 (0.43) | EPHX2ALDH1A1MAPTHSD11B1NFE2L2 | |
| SCHEMBL1313342 | 0.73 | EPHX2 (0.47) | EPHX2MAPTHSD11B1NFE2L2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-4995898-A | Imidazole compounds and biocidal composition comprising the same for controlling harmful organisms | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1991-02-26 | — | — | US | disclosed |