Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 11/20 | 0.45 |
| ▸ | DRD2 | P14416 | 10/20 | 0.45 |
| ▸ | DRD4 | P21917 | 10/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499273 | 0.83 | SLC6A1 (0.52) | SLC6A1DRD3DRD2DRD4CHRM1 | |
| Potassium Ion SCHEMBL6957972 | 0.80 | CHRM2 (0.47) | SLC6A1DRD3DRD2DRD4CHRM1 | |
| SCHEMBL8202612 | 0.79 | SLC6A1 (0.61) | SLC6A1DRD3DRD2DRD4CHRM1 | |
| SCHEMBL8206721 | 0.79 | SLC6A1 (0.61) | SLC6A1DRD3DRD2DRD4CHRM1 | |
| SCHEMBL6968012 | 0.79 | SLC6A1 (0.50) | SLC6A1DRD3DRD2DRD4CHRM1 | |
| SCHEMBL6963416 | 0.78 | CHRM1 (0.58) | DRD3DRD2DRD4CHRM1CHRM2 | |
| SCHEMBL6968389 | 0.78 | SLC6A1 (0.49) | SLC6A1DRD3DRD2DRD4CHRM1 | |
| SCHEMBL6954568 | 0.78 | DRD3 (0.46) | SLC6A1DRD3DRD2DRD4CHRM1 | |
| SCHEMBL8206888 | 0.77 | SLC6A1 (0.61) | SLC6A1DRD3DRD2DRD4 | |
| SCHEMBL8202368 | 0.76 | SLC6A1 (0.57) | SLC6A1DRD3DRD2DRD4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820451-B1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2003-01-15 | — | — | EP | claimed |