SCHEMBL69673

SCHEMBL69673

O=C(O)c1ccc(C(=O)O)c2ncccc12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.77
L3MBTL1 Q9Y468 3/20 0.77
KDM4A O75164 2/20 0.77
EGLN1 Q9GZT9 2/20 0.77
KDM6B O15054 1/20 0.77
KDM6A O15550 1/20 0.77
TET3 O43151 1/20 0.77
KDM4B O94953 1/20 0.77
KDM5C P41229 1/20 0.77
KDM4D Q6B0I6 1/20 0.77
TET2 Q6N021 1/20 0.77
ALKBH5 Q6P6C2 1/20 0.77
TET1 Q8NFU7 1/20 0.77
FTO Q9C0B1 1/20 0.77
KDM4C Q9H3R0 1/20 0.77
KDM2A Q9Y2K7 1/20 0.77
KDM3A Q9Y4C1 1/20 0.77
RAB9A P51151 1/20 0.61
HIF1AN Q9NWT6 1/20 0.61
PSMD14 O00487 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6068195 0.87 KDM4E (1.00) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL29349767 0.87 KDM4E (1.00) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL11261836 0.87 KDM4E (0.75) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL69905 0.86 KDM4E (0.74) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL6962756 0.85 KDM4E (0.68) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL3899127 0.85 KDM4E (0.68) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL5306342 0.85 KDM4E (0.59) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL1126280 0.85 KMT2A (0.62) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL11803761 0.85 SLC6A2 (0.59) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL15703127 0.85 KDM4E (0.68) KDM4EL3MBTL1KDM4AEGLN1KDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-4968803-A FLUORINE AS OXIDANT ALLIED-SIGNAL INC. (US) 1990-11-06 US disclosed
US-4093622-A Pyridine esters of cyclopropane-carboxylic acid ZOECON CORPORATION (US) 1978-06-06 US disclosed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 KDM4E 717/4885L3MBTL1 4274/4885KDM4A 169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.