SCHEMBL11261836

SCHEMBL11261836

O=C(O)c1ccc(O)c2cccnc12

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.75
L3MBTL1 Q9Y468 5/20 0.75
KDM4A O75164 2/20 0.75
EGLN1 Q9GZT9 2/20 0.75
FTO Q9C0B1 2/20 0.75
KDM6B O15054 1/20 0.75
KDM6A O15550 1/20 0.75
TET3 O43151 1/20 0.75
KDM4B O94953 1/20 0.75
KDM5C P41229 1/20 0.75
KDM4D Q6B0I6 1/20 0.75
TET2 Q6N021 1/20 0.75
ALKBH5 Q6P6C2 1/20 0.75
TET1 Q8NFU7 1/20 0.75
KDM4C Q9H3R0 1/20 0.75
KDM2A Q9Y2K7 1/20 0.75
KDM3A Q9Y4C1 1/20 0.75
ALDH1A1 P00352 3/20 0.56
RAB9A P51151 3/20 0.56
HIF1AN Q9NWT6 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69673 0.87 KDM4E (0.77) KDM4EL3MBTL1KDM4AEGLN1FTO
SCHEMBL7691980 0.86 KDM4E (0.65) KDM4EL3MBTL1KDM4AEGLN1FTO
SCHEMBL31466724 0.86 KDM4E (0.65) KDM4EL3MBTL1KDM4AEGLN1FTO
SCHEMBL6068195 0.86 KDM4E (1.00) KDM4EL3MBTL1KDM4AEGLN1FTO
SCHEMBL29349767 0.86 KDM4E (1.00) KDM4EL3MBTL1KDM4AEGLN1FTO
SCHEMBL11803761 0.81 SLC6A2 (0.59) KDM4EL3MBTL1KDM4AEGLN1FTO
SCHEMBL30503371 0.81 SLC6A2 (0.59) KDM4EL3MBTL1KDM4AEGLN1FTO
SCHEMBL1126280 0.81 KMT2A (0.62) KDM4EL3MBTL1KDM4AEGLN1FTO
SCHEMBL29848459 0.81 HSP90AA1 (0.59) KDM4EL3MBTL1KDM4AEGLN1FTO
SCHEMBL5306342 0.81 KDM4E (0.59) KDM4EL3MBTL1KDM4AEGLN1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014553-B1 PROCESS FOR PURIFYING RARE-EARTH COMPOSITIONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-05-05 EP disclosed
US-4265862-A FROM RADIOACTIVE IMPURITIES EASTMAN KODAK COMPANY (US) 1981-05-05 US disclosed
EP-0014553-A1 Process for purifying rare-earth compositions EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-08-20 EP disclosed