Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696829 | 0.87 | TAAR1 (0.44) | TAAR1CYP19A1PARP1CYP3A4CYP2D6 | |
| SCHEMBL697435 | 0.85 | CYP19A1 (0.46) | TAAR1CYP19A1PARP1HSD17B10 | |
| SCHEMBL1573181 | 0.84 | CYP19A1 (0.40) | TAAR1CYP19A1MTORADKNISCH | |
| SCHEMBL6299558 | 0.84 | CYP19A1 (0.46) | TAAR1CYP19A1CYP1A2CYP3A4KMT2A | |
| SCHEMBL696761 | 0.81 | TAAR1 (0.40) | TAAR1CYP19A1PARP1HSD11B1 | |
| SCHEMBL706070 | 0.79 | CYP19A1 (0.48) | TAAR1CYP19A1CYP1A2CYP3A4KMT2A | |
| SCHEMBL697917 | 0.79 | CYP19A1 (0.38) | TAAR1CYP19A1HSD11B1 | |
| SCHEMBL697634 | 0.78 | CYP19A1 (0.37) | TAAR1CYP19A1ALDH1A1 | |
| SCHEMBL698787 | 0.78 | CYP19A1 (0.43) | TAAR1CYP19A1ALDH1A1KMT2ALMNA | |
| SCHEMBL697452 | 0.78 | CYP19A1 (0.49) | TAAR1CYP19A1KMT2AMEN1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |