Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 7/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976723 | 0.85 | LTA4H (0.55) | TSHRKCNH2LTA4H | |
| SCHEMBL17682060 | 0.85 | TSHR (0.81) | TSHRMAOBATMMEN1KMT2A | |
| SCHEMBL11681713 | 0.82 | TSHR (0.77) | TSHRMAOBATMMEN1KMT2A | |
| SCHEMBL7451250 | 0.82 | ALDH1A1 (0.58) | TSHRMAOBKCNH2LTA4H | |
| SCHEMBL4748572 | 0.81 | ALDH1A1 (0.60) | TSHRMAOB | |
| SCHEMBL5216661 | 0.81 | TSHR (0.71) | TSHRMAOBATMMEN1KMT2A | |
| SCHEMBL8430091 | 0.81 | TSHR (0.75) | TSHRMAOBATMMEN1KMT2A | |
| SCHEMBL15226786 | 0.81 | TSHR (0.75) | TSHRMAOBATMMEN1KMT2A | |
| SCHEMBL8791474 | 0.81 | TSHR (0.75) | TSHRMAOBATMMAOAMEN1 | |
| SCHEMBL14569771 | 0.80 | TSHR (0.69) | TSHRATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | disclosed |
| EP-0801063-A1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-10-15 | — | — | EP | disclosed |