Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300253 | 0.86 | ALDH1A1 (0.42) | PTGS1FAAHALDH1A1MAPTTAS1R3 | |
| SCHEMBL6972696 | 0.84 | PTGS1 (0.37) | PTGS1ALDH1A1MAPT | |
| SCHEMBL11121776 | 0.80 | ALDH1A1 (0.54) | PTGS1FAAHALDH1A1MAPT | |
| SCHEMBL11121777 | 0.80 | ALDH1A1 (0.54) | PTGS1FAAHALDH1A1MAPT | |
| SCHEMBL3299574 | 0.80 | TAS1R3 (0.39) | PTGS1FAAHALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL3300822 | 0.80 | TAS1R3 (0.39) | PTGS1FAAHALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL6973672 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL6967055 | 0.78 | — | — | |
| SCHEMBL6967723 | 0.76 | PTGS1 (0.31) | PTGS1FAAH | |
| SCHEMBL6967726 | 0.76 | PTGS1 (0.31) | PTGS1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |