SCHEMBL69678

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL68814	0.83	KDM4E (0.58)	ALDH1A1HDAC8HDAC3HDAC4HDAC2
	SCHEMBL13871409	0.76	EPHX2 (0.53)	ALDH1A1KDM4EMEN1KMT2AHTT
	SCHEMBL13539308	0.72	KDM4E (0.38)	KDM4EHTTMAOAMAOB
	SCHEMBL9159671	0.72	VHL (0.49)	KDM4EMAPTMEN1KMT2AL3MBTL1
	SCHEMBL2594793	0.72	S100A4 (0.43)	HDAC8KDM4EL3MBTL1HTTCA1
	SCHEMBL69685	0.71	KDM4E (0.38)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL14430028	0.69	ALDH1A1 (0.53)	ALDH1A1KDM4EMAPTMEN1KMT2A
	SCHEMBL91643	0.67	AKR1B1 (0.43)	ALDH1A1KDM4EMAPTMEN1MAPK1
	SCHEMBL10926086	0.66	ALDH1A1 (0.59)	ALDH1A1KDM4EMEN1MAPK1KMT2A
	SCHEMBL9514250	0.66	ALDH1A1 (0.59)	ALDH1A1KDM4EMAPTMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.