Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962593 | 0.89 | RBP4 (0.61) | KMT2AKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL6966945 | 0.89 | MAPT (0.57) | KDM4EHSD17B10ALDH1A1MAPTMAPK1 | |
| SCHEMBL6965818 | 0.88 | MAPT (0.58) | KMT2AKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL6966427 | 0.88 | KMT2A (0.60) | KMT2AKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL8700515 | 0.87 | KDM4E (0.48) | KMT2AKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL6960999 | 0.86 | KDM4E (0.52) | KMT2AKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL7139727 | 0.86 | RBP4 (0.46) | KMT2AKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL8699044 | 0.84 | KDM4E (0.51) | KMT2AKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL27467044 | 0.84 | RBP4 (0.43) | KMT2AKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL27467994 | 0.84 | KMT2A (0.64) | KMT2AKDM4EHSD17B10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152015-C | Piperazine devivatives and process for preparation thereof | ������ҩ��ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |
| CN-1196724-A | Novel piperazine derivative and process for producing the same | SAMJIN PHARM CO LTD (KR) | 1998-10-21 | — | — | CN | disclosed |
| EP-0850222-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 1998-07-01 | — | — | EP | disclosed |
| WO-1998000402-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-01-08 | — | — | WO | disclosed |