Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967897 | 0.88 | KMT2A (0.49) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL6952726 | 0.88 | MAPT (0.55) | MAPTLMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL8705827 | 0.87 | LMNA (0.61) | MAPTLMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL6966945 | 0.87 | MAPT (0.57) | MAPTLMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL6962593 | 0.87 | RBP4 (0.61) | MAPTLMNAALDH1A1MAPK1KMT2A | |
| SCHEMBL6966427 | 0.86 | KMT2A (0.60) | MAPTALDH1A1TSHRMAPK1MEN1 | |
| SCHEMBL6955958 | 0.85 | MAPT (0.48) | MAPTLMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL7139727 | 0.84 | RBP4 (0.46) | MAPTALDH1A1TSHRMAPK1MEN1 | |
| SCHEMBL8700061 | 0.83 | MAPT (0.57) | MAPTLMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL7139732 | 0.83 | RBP4 (0.43) | MAPTALDH1A1TSHRMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |