Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 10/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955812 | 0.89 | GRIN2B (0.55) | GRIN2BTAAR1GRIN1 | |
| SCHEMBL6972183 | 0.85 | GRIN2B (0.47) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL6974030 | 0.85 | TAAR1 (0.40) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL224352 | 0.81 | DAO (0.41) | TAAR1 | |
| SCHEMBL6965589 | 0.80 | GRIN2B (0.44) | GRIN2BTAAR1GRIN1 | |
| SCHEMBL6970991 | 0.79 | GRIN2B (0.51) | GRIN2BTAAR1GRIN1HTR3EHTR3B | |
| SCHEMBL6973014 | 0.78 | GRIN2B (0.55) | GRIN2BGRIN1 | |
| SCHEMBL6968291 | 0.77 | GRIN2B (0.42) | GRIN2BGRIN1 | |
| SCHEMBL6958768 | 0.77 | GRIN2B (0.42) | GRIN2BTAAR1GRIN1HRH4HRH3 | |
| SCHEMBL6972377 | 0.77 | GRIN2B (0.42) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |