Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 13/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.55 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955812 | 0.89 | GRIN2B (0.55) | GRIN2BGRIN1 | |
| SCHEMBL6973872 | 0.89 | GRIN2B (0.40) | GRIN2BGRIN1 | |
| SCHEMBL6961034 | 0.88 | GRIN2B (0.57) | GRIN2BGRIN1PLA2G10PLA2G2A | |
| SCHEMBL6965898 | 0.85 | GRIN2B (0.55) | GRIN2BGRIN1 | |
| SCHEMBL6972539 | 0.85 | GRIN2B (0.57) | GRIN2BGRIN1 | |
| SCHEMBL6967752 | 0.85 | GRIN2B (0.42) | GRIN2BGRIN1NOS2 | |
| SCHEMBL6970991 | 0.81 | GRIN2B (0.51) | GRIN2BGRIN1 | |
| SCHEMBL649075 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL6968091 | 0.78 | GRIN2B (0.53) | GRIN2BGRIN1 | |
| SCHEMBL6969109 | 0.76 | GRIN2B (0.55) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0729459-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014007-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |