Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | PIM1 | P11309 | 2/20 | 0.58 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968829 | 1.00 | PPARG (0.60) | PPARGHPGDPIM1PIM2PTPN1 | |
| SCHEMBL6966749 | 0.84 | HPGD (0.69) | PPARGHPGDPIM1PIM2PTPN1 | |
| SCHEMBL6966747 | 0.84 | HPGD (0.69) | PPARGHPGDPIM1PIM2PTPN1 | |
| SCHEMBL9327166 | 0.82 | PPARG (0.80) | PPARGHPGDPIM1PIM2PTPN1 | |
| SCHEMBL9327162 | 0.82 | PPARG (0.80) | PPARGHPGDPIM1PIM2PTPN1 | |
| SCHEMBL6969911 | 0.81 | HPGD (0.78) | PPARGHPGDPIM1PIM2PTPN1 | |
| SCHEMBL6969914 | 0.81 | HPGD (0.78) | PPARGHPGDPIM1PIM2PTPN1 | |
| SCHEMBL6971511 | 0.80 | MAOB (0.49) | PPARGHPGDMAOB | |
| SCHEMBL6971515 | 0.80 | MAOB (0.49) | PPARGHPGDMAOB | |
| SCHEMBL9326976 | 0.79 | HPGD (0.80) | HPGDPIM1PIM2PTPN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | claimed |
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | disclosed |
| EP-0801063-A1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-10-15 | — | — | EP | disclosed |