Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6965930 | 0.99 | GPR6 (0.37) | GPR6MEN1KMT2APRKAA2DHFR | |
| SCHEMBL6969559 | 0.94 | MEN1 (0.37) | GPR6MEN1KMT2APRKAA2DHFR | |
| Hydrochloric Acid SCHEMBL6968128 | 0.88 | ATM (0.35) | MEN1KMT2ADHFRMAPTSMN1; SMN2 | |
| SCHEMBL6957847 | 0.88 | GRIN1 (0.36) | LMNATP53 | |
| SCHEMBL6961412 | 0.85 | SMN1; SMN2 (0.37) | KMT2AMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL6958886 | 0.85 | POLB (0.38) | KMT2AMAPTLMNAPOLBTP53 | |
| SCHEMBL6965486 | 0.84 | KMT2A (0.37) | MEN1KMT2AMAPTSMN1; SMN2CYP2C9 | |
| SCHEMBL6962260 | 0.84 | SLC2A1 (0.40) | KMT2AMAPTLMNACYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6967948 | 0.84 | MC4R (0.34) | DHFRLMNATP53 | |
| Hydrochloric Acid SCHEMBL6967954 | 0.84 | MC4R (0.34) | DHFRLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |