Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960659 | 0.95 | POLB (0.38) | POLBMAPTLMNAPDGFRBPDGFRA | |
| SCHEMBL6962260 | 0.94 | SLC2A1 (0.40) | MAPTLMNAPDGFRBPDGFRAKCNH3 | |
| SCHEMBL6962677 | 0.88 | SLC2A1 (0.40) | MAPTPDGFRBPDGFRAKCNH3KMT2A | |
| SCHEMBL6956604 | 0.87 | KMT2A (0.35) | MAPTPDGFRBPDGFRAKMT2ATP53 | |
| Hydrochloric Acid SCHEMBL6964992 | 0.86 | CA1 (0.40) | POLBMAPTLMNAPDGFRBPDGFRA | |
| SCHEMBL6957847 | 0.86 | GRIN1 (0.36) | GHSRLMNAKCNH3TP53RORC | |
| SCHEMBL6967118 | 0.86 | KCNH3 (0.36) | POLBMAPTPDGFRBPDGFRAKCNH3 | |
| SCHEMBL6965486 | 0.85 | KMT2A (0.37) | MAPTPDGFRBPDGFRAKMT2ATP53 | |
| SCHEMBL6968906 | 0.85 | GPR6 (0.38) | POLBMAPTLMNAKMT2ATP53 | |
| SCHEMBL6957796 | 0.85 | MAPT (0.35) | MAPTLMNAPDGFRBPDGFRAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |