Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962677 | 0.94 | SLC2A1 (0.40) | SLC2A1KLK7EGFRFYNPDGFRB | |
| SCHEMBL6958886 | 0.94 | POLB (0.38) | EGFRFYNPDGFRBFGFR1PDGFRA | |
| SCHEMBL6956604 | 0.89 | KMT2A (0.35) | EGFRFYNPDGFRBFGFR1PDGFRA | |
| SCHEMBL6960659 | 0.89 | POLB (0.38) | SLC2A1EGFRFYNPDGFRBFGFR1 | |
| SCHEMBL6965486 | 0.87 | KMT2A (0.37) | EGFRFYNPDGFRBFGFR1PDGFRA | |
| Hydrochloric Acid SCHEMBL6964992 | 0.87 | CA1 (0.40) | EGFRFYNPDGFRBFGFR1PDGFRA | |
| SCHEMBL6957796 | 0.87 | MAPT (0.35) | EGFRFYNPDGFRBFGFR1PDGFRA | |
| SCHEMBL6962244 | 0.87 | KMT2A (0.35) | EGFRFYNPDGFRBFGFR1PDGFRA | |
| SCHEMBL6967118 | 0.86 | KCNH3 (0.36) | PDGFRBPDGFRAKMT2AKCNH3MAPT | |
| SCHEMBL6957959 | 0.86 | SMN1; SMN2 (0.38) | KMT2AMAPTNPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |