Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | DRD4 | P21917 | 6/20 | 0.53 |
| ▸ | DRD3 | P35462 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10745573 | 0.90 | GAA (0.58) | DRD2DRD4DRD3GAAL3MBTL1 | |
| SCHEMBL16808226 | 0.84 | DRD2 (0.63) | DRD2DRD4DRD3GAAALDH1A1 | |
| SCHEMBL3805304 | 0.80 | DRD2 (0.68) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL5929468 | 0.80 | DRD2 (0.68) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL25433144 | 0.80 | DRD2 (0.53) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL14844426 | 0.80 | LTA4H (0.53) | DRD2DRD4DRD3GAA | |
| SCHEMBL6746156 | 0.80 | GAA (0.47) | GAAALDH1A1 | |
| SCHEMBL21051903 | 0.80 | DRD2 (0.53) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL6437358 | 0.80 | GAA (0.47) | DRD2DRD4DRD3GAAL3MBTL1 | |
| SCHEMBL7501215 | 0.79 | KCNA3 (0.62) | DRD2DRD4DRD3GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848004-B1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5955616-A | PROSTAGLANDIN INHIBITORS | SHIONOGI & CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0848004-A1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |