Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL21812140 | 0.88 | ALDH1A1 (0.62) | HCRTR1L3MBTL1GLAMAPTGAA | |
| Benzene SCHEMBL28074659 | 0.88 | ALDH1A1 (0.62) | HCRTR1L3MBTL1GLAMAPTGAA | |
| Bicarbonate SCHEMBL29943568 | 0.88 | ALDH1A1 (0.62) | HCRTR1L3MBTL1GLAMAPTGAA | |
| Bicarbonate SCHEMBL237486 | 0.88 | ALDH1A1 (0.62) | HCRTR1L3MBTL1GLAMAPTGAA | |
| SCHEMBL11763044 | 0.88 | HCRTR1 (0.66) | HCRTR1L3MBTL1GLAMAPTGAA | |
| SCHEMBL206583 | 0.88 | HCRTR1 (0.66) | HCRTR1L3MBTL1GLAMAPTGAA | |
| SCHEMBL30292656 | 0.86 | LMNA (0.71) | HCRTR1L3MBTL1GLAMAPTGAA | |
| SCHEMBL335970 | 0.86 | LMNA (0.71) | HCRTR1L3MBTL1GLAMAPTGAA | |
| Benzene SCHEMBL27314454 | 0.86 | ALDH1A1 (0.65) | HCRTR1L3MBTL1GLAMAPTGAA | |
| SCHEMBL124831 | 0.86 | ALDH1A1 (0.65) | HCRTR1L3MBTL1GLAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |