Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12168364 | 0.76 | TSHR (0.46) | TSHRALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL29091864 | 0.73 | TSHR (0.94) | TSHRALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL27380 | 0.71 | TSHR (1.00) | TSHRALDH1A1KDM4EPOLBLMNA | |
| Benzene SCHEMBL27997624 | 0.71 | TSHR (1.00) | TSHRALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL5311581 | 0.71 | TSHR (1.00) | TSHRALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL30239567 | 0.70 | TSHR (0.50) | TSHRL3MBTL1KDM4EPOLBMAPT | |
| Toluene SCHEMBL19206951 | 0.69 | TSHR (0.75) | TSHRALDH1A1L3MBTL1KDM4EPOLB | |
| P-Xylene SCHEMBL19206957 | 0.69 | TSHR (0.75) | TSHRALDH1A1L3MBTL1KDM4EPOLB | |
| O-Xylene SCHEMBL19206943 | 0.69 | TSHR (0.75) | TSHRALDH1A1L3MBTL1KDM4EPOLB | |
| Propane SCHEMBL11584021 | 0.69 | TSHR (0.83) | TSHRALDH1A1L3MBTL1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930305-B1 | 1,2,3-THIADIAZOLE DERIVATIVES AND SALTS THEREOF, DISEASE CONTROLLING AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE, AND METHOD FOR THE USE THEREOF | NIHON NOHYAKU CO LTD (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6337341-B1 | AGROHORTICULTURAL DISEASE CONTROLLER CONTAINING SAID COMPOUND AS AN ACTIVE INGREDIENT, AND METHOD FOR USING THE DISEASE CONTROLLER. | NIHON NOHYAKU CO., LTD. (JP) | 2002-01-08 | — | — | US | disclosed |
| CN-1072657-C | 1,2, 3-thiadiazole derivative and salt thereof, agrohorticultural virus control agent, and method for using same | NIHON NOHYAKU CO LTD (JP) | 2001-10-10 | — | — | CN | disclosed |
| US-6194444-B1 | FUNGICIDES, BACTERICIDES, VIRICIDES | NIHON NOHYAKU CO., LTD (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-0930305-A1 | 1,2,3-THIADIAZOLE DERIVATIVES AND SALTS THEREOF, DISEASE CONTROLLING AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE, AND METHOD FOR THE USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |