Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7344269 | 0.86 | MEN1 (0.42) | ALDH1A1MEN1KMT2ANOTUMNPSR1 | |
| SCHEMBL7256718 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AAVPR1AAVPR2 | |
| SCHEMBL5250240 | 0.77 | CHRM2 (0.60) | ALDH1A1MEN1KMT2ANOTUMLMNA | |
| SCHEMBL5232142 | 0.77 | MAPT (0.42) | ALDH1A1MEN1KMT2AAVPR1AAVPR2 | |
| SCHEMBL6971065 | 0.76 | NPSR1 (0.56) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL13477747 | 0.75 | MEN1 (0.54) | ALDH1A1MEN1KMT2ALMNAAVPR1A | |
| SCHEMBL5848149 | 0.74 | KMT2A (0.46) | ALDH1A1MEN1KMT2ANOTUMNPSR1 | |
| SCHEMBL26109852 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ANOTUMNPSR1 | |
| SCHEMBL5660336 | 0.74 | NOTUM (0.61) | ALDH1A1MEN1KMT2ANOTUMMAPT | |
| SCHEMBL3094477 | 0.74 | AVPR1A (0.55) | ALDH1A1NOTUMAVPR1AAVPR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |