Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025475 | 0.81 | MEN1 (0.53) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5234944 | 0.80 | BRPF1 (0.50) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11231189 | 0.79 | NPSR1 (0.61) | NPSR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1759599 | 0.78 | ALOX15 (0.49) | NPSR1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6969092 | 0.76 | ALDH1A1 (0.47) | NPSR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11493458 | 0.75 | CHRM2 (0.50) | ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL19755832 | 0.74 | NPSR1 (0.55) | NPSR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18072430 | 0.73 | NPSR1 (0.54) | NPSR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3425056 | 0.73 | NPSR1 (0.57) | NPSR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18825277 | 0.73 | GSK3A (0.61) | NPSR1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |