Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.53 |
| ▸ | ITGAV | P06756 | 16/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7659068 | 0.99 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5CASP1 | |
| SCHEMBL6964129 | 0.93 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7651509 | 0.92 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB5CASP1 | |
| SCHEMBL6969100 | 0.85 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5CASP1 | |
| Hydrochloric Acid SCHEMBL7230730 | 0.85 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB5CASP1 | |
| SCHEMBL6978381 | 0.83 | ITGB3 (0.48) | ITGB3ITGAVITGA2B | |
| SCHEMBL7216234 | 0.80 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7216236 | 0.80 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6972652 | 0.80 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL6977082 | 0.79 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586442-B2 | Benzofurane derivatives, their preparation process, their use as medicaments and the pharmaceutical compositions containing them | CARNIATO DENIS (FR) | 2003-07-01 | — | — | US | claimed |
| EP-1133491-B1 | NOVEL BENZOFURANE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2003-02-19 | — | — | EP | claimed |
| US-6458801-B1 | PHARMACEUTICALLY ACCEPTABLE SALTS AND ITS PRODRUG USEFUL FOR TREATING OSTEOPOROSIS. | AVENTIS PHARMA S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6586442-B2 | Benzofurane derivatives, their preparation process, their use as medicaments and the pharmaceutical compositions containing them | CARNIATO DENIS (FR) | 2003-07-01 | — | — | US | disclosed |
| US-20020187976-A1 | New benzofurane derivatives, their preparation process, their use as medicaments and the pharmaceutical compositions containing them | AVENTIS PHARMA S.A. | 2002-12-12 | — | — | US | disclosed |
| US-6458801-B1 | PHARMACEUTICALLY ACCEPTABLE SALTS AND ITS PRODRUG USEFUL FOR TREATING OSTEOPOROSIS. | AVENTIS PHARMA S.A. (FR) | 2002-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020187976-A1 | New benzofurane derivatives, their preparation process, their use as medicaments and the pharmaceutical compositions containing them | CYP2F1, CYP2C19, CYP2B6 | ITGB3 3038/4885ITGAV 3583/4885ITGA2B 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.