SCHEMBL6969187

SCHEMBL6969187

Clc1ccc(OCCC2CCc3[nH]cnc3C2)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 16/20 0.43
WDR5 P61964 1/20 0.40
ADRA1A P35348 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6967534 0.99 S1PR4 (0.43) S1PR4WDR5ADRA1A
SCHEMBL6957422 0.76 SLC6A4 (0.40) ADRA1A
SCHEMBL6963397 0.75 HTR1B (0.41) ADRA1A
SCHEMBL6954587 0.75 ADRA1A (0.48) ADRA1A
Hydrochloric Acid SCHEMBL6967610 0.74 HTR1B (0.40) ADRA1A
SCHEMBL6960436 0.73 LMNA (0.40) ADRA1A
SCHEMBL6967355 0.72 ADRA1A (0.49) ADRA1A
Hydrochloric Acid SCHEMBL6963559 0.70 ADRA1A (0.40) ADRA1A
SCHEMBL11413525 0.69 S1PR4 (0.66) S1PR4
SCHEMBL6961383 0.67 HRH3 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6610721-B2 Imidazo heterocyclic compounds NOVO NORDISK A/S (DK) 2003-08-26 US disclosed
EP-1268483-A1 CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS NOVO NORDISK A/S (DK) 2003-01-02 EP disclosed
US-20010049385-A1 Imidazo heterocyclic compounds HIGH POINT PHARMACEUTICALS, LLC 2001-12-06 US disclosed
WO-2001068651-A1 CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS NOVO NORDISK A/S (DK) 2001-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010049385-A1 Imidazo heterocyclic compounds HRH4, HRH3, HRH2 S1PR4 1068/4885WDR5 914/4885ADRA1A 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.