Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094293 | 0.82 | MEN1 (0.69) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL3606616 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL650892 | 0.80 | MEN1 (0.56) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL11441580 | 0.80 | MEN1 (0.56) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10710090 | 0.79 | MEN1 (0.79) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL9835974 | 0.78 | MEN1 (0.69) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL665304 | 0.78 | MEN1 (0.69) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL11541462 | 0.77 | ALDH1A1 (0.58) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| Fluoride SCHEMBL11789630 | 0.76 | MEN1 (0.67) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL2008072 | 0.76 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |