SCHEMBL6969379

SCHEMBL6969379

CCCc1sc(OC(=O)O)cc1F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.34
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5888342 0.75 DAO (0.40) HCAR2
SCHEMBL7505061 0.69 RECQL (0.35) ALOX5
SCHEMBL5887962 0.67 CYP2A6 (0.32)
SCHEMBL5588399 0.65 LDHA (0.38) ALOX5HCAR2
SCHEMBL5046977 0.64 GPR35 (0.33)
SCHEMBL9176677 0.64 MAPT (0.52)
SCHEMBL6231392 0.62 LDHA (0.36) ALOX5HCAR2
SCHEMBL5233818 0.62 CHRNA7 (0.39)
SCHEMBL10882465 0.61 DAO (0.55)
SCHEMBL14037669 0.61 RARB (0.43) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1214316-B1 FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES CLARIANT INT LTD (CH) 2003-05-07 EP disclosed
EP-1214316-A1 FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES CLARIANT INTERNATIONAL LTD. (CH) 2002-06-19 EP disclosed
WO-2001016131-A2 FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES CLARIANT INTERNATIONAL LTD (CH) 2001-03-08 WO disclosed