Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978114 | 0.92 | PTGS2 (0.51) | PTGS2KCNH2MEN1KMT2AL3MBTL1 | |
| SCHEMBL6975319 | 0.91 | CA1 (0.53) | PTGS2KCNH2MEN1KMT2AL3MBTL1 | |
| SCHEMBL6973977 | 0.88 | PTGS2 (0.53) | PTGS2PTGS1TDO2 | |
| SCHEMBL6978281 | 0.88 | L3MBTL1 (0.57) | PTGS2KCNH2MEN1KMT2AL3MBTL1 | |
| SCHEMBL6973900 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL6977438 | 0.83 | CA1 (0.53) | PTGS2KCNH2MEN1KMT2AL3MBTL1 | |
| SCHEMBL6972454 | 0.82 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6971876 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL6975494 | 0.79 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6981008 | 0.78 | L3MBTL1 (0.56) | PTGS2MEN1KMT2AL3MBTL1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | claimed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | claimed |
| CN-1323301-A | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORP (KR) | 2001-11-21 | — | — | CN | claimed |
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |
| CN-1323301-A | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORP (KR) | 2001-11-21 | — | — | CN | disclosed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | disclosed |