Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557855 | 0.88 | TSHR (0.36) | CRBNKDM4ELMNAKMT2ATSHR | |
| SCHEMBL30480733 | 0.84 | MAPT (0.33) | CRBNRAB9AKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6982039 | 0.84 | MAPT (0.33) | CRBNRAB9AKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL29899213 | 0.72 | CHRNB4 (0.51) | RAB9ASMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL700713 | 0.71 | CD44 (0.39) | KDM4ETDP1TSHR | |
| SCHEMBL10343777 | 0.69 | — | — | |
| SCHEMBL28429620 | 0.69 | ALDH1A1 (0.36) | — | |
| SCHEMBL570014 | 0.68 | CHRNB4 (0.42) | RAB9AKDM4ELMNASMN1; SMN2TDP1 | |
| SCHEMBL10748015 | 0.68 | NPC1 (0.30) | — | |
| SCHEMBL29899212 | 0.68 | HTR2B (0.40) | CRBNRAB9AKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018193387-A1 | HETEROCYCLIC COMPOUNDS WITH MICROBIOCIDAL PROPERTIES | PI INDUSTRIES LTD. (IN) | 2018-10-25 | — | — | WO | claimed |
| EP-0966452-B1 | PROCESS FOR PREPARING SULPHUROUS 2-CHLORO-3-(4,5-DIHYDROISOXAZOL-3-YL)-BENZOIC ACIDS | BASF AG (DE) | 2003-05-02 | — | — | EP | claimed |
| US-6124469-A | Process for preparing sulphurous 2-chloro-3-(4,5-dihydroisoxazol-3-yl)-benzoic acids | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-26 | — | — | US | claimed |
| EP-0966452-B1 | PROCESS FOR PREPARING SULPHUROUS 2-CHLORO-3-(4,5-DIHYDROISOXAZOL-3-YL)-BENZOIC ACIDS | BASF AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6124469-A | Process for preparing sulphurous 2-chloro-3-(4,5-dihydroisoxazol-3-yl)-benzoic acids | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-26 | — | — | US | disclosed |