Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700713 | 0.81 | CD44 (0.39) | ACHE | |
| SCHEMBL31040435 | 0.81 | CD44 (0.39) | ACHE | |
| SCHEMBL27484510 | 0.80 | — | — | |
| SCHEMBL6666084 | 0.79 | — | — | |
| SCHEMBL6382453 | 0.79 | — | — | |
| SCHEMBL30480757 | 0.78 | ALOX15 (0.31) | ALDH1A1 | |
| SCHEMBL29462230 | 0.75 | L3MBTL1 (0.33) | — | |
| SCHEMBL30315779 | 0.74 | TSHR (0.46) | ALDH1A1ACHE | |
| SCHEMBL8626370 | 0.72 | CRBN (0.41) | ALDH1A1PBRM1 | |
| SCHEMBL4537402 | 0.71 | ALDH1A1 (0.60) | ALDH1A1PBRM1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652246-B | Preparation method of 3- [ 3-bromo-2-methyl-6- (methylsulfonyl) phenyl ] -4, 5-dihydro isoxazole | 江苏乾元生物科技有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-111440160-A | Preparation method and application of topramezone | 黑龙江省绥化农垦晨环生物制剂有限责任公司 | 2020-07-24 | — | — | CN | claimed |
| CN-107652246-B | Preparation method of 3- [ 3-bromo-2-methyl-6- (methylsulfonyl) phenyl ] -4, 5-dihydro isoxazole | 江苏乾元生物科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-111440160-A | Preparation method and application of topramezone | 黑龙江省绥化农垦晨环生物制剂有限责任公司 | 2020-07-24 | — | — | CN | disclosed |