Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968538 | 0.86 | — | — | |
| SCHEMBL28855159 | 0.74 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHR | |
| SCHEMBL6968542 | 0.73 | — | — | |
| SCHEMBL6965014 | 0.72 | — | — | |
| SCHEMBL19432260 | 0.69 | KMT2A (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6594467 | 0.69 | — | — | |
| SCHEMBL6593404 | 0.67 | — | — | |
| SCHEMBL1169645 | 0.67 | — | — | |
| SCHEMBL9453791 | 0.67 | LMNA (0.34) | SMN1; SMN2 | |
| SCHEMBL11465292 | 0.67 | TSHR (0.46) | SMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |