Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | USP2 | O75604 | 4/20 | 0.68 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.50 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970555 | 1.00 | MEN1 (0.68) | MEN1KMT2AALDH1A1USP2BCL2L1 | |
| SCHEMBL6957011 | 0.94 | MEN1 (0.68) | MEN1KMT2AALDH1A1USP2BCL2L1 | |
| SCHEMBL6966702 | 0.87 | MEN1 (0.69) | MEN1KMT2AALDH1A1USP2POLB | |
| SCHEMBL6966699 | 0.87 | MEN1 (0.69) | MEN1KMT2AALDH1A1USP2POLB | |
| SCHEMBL6969428 | 0.83 | ALDH1A1 (0.77) | MEN1KMT2AALDH1A1USP2BCL2L1 | |
| SCHEMBL6969430 | 0.83 | ALDH1A1 (0.77) | MEN1KMT2AALDH1A1USP2BCL2L1 | |
| SCHEMBL6964099 | 0.83 | MEN1 (0.61) | MEN1KMT2AALDH1A1USP2POLB | |
| SCHEMBL6964104 | 0.83 | MEN1 (0.61) | MEN1KMT2AALDH1A1USP2POLB | |
| SCHEMBL6970225 | 0.82 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1USP2BCL2L1 | |
| SCHEMBL6970226 | 0.82 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1USP2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1173964-C | Novel benzofuranone derivative and process for producing same | ��һ��������ҩ��ʽ���� | 2004-11-03 | — | — | CN | disclosed |
| EP-0902022-B1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6143779-A | Benzofuranone derivatives and a method for producing them | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| CN-1217719-A | Novel benzofuranone derivative and process for producing the same | SNOW BRAND MILK PRODUCTS CO LTD (JP) | 1999-05-26 | — | — | CN | disclosed |
| EP-0902022-A1 | NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |