Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875786 | 0.80 | HPGD (0.59) | HSD17B10ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL10513977 | 0.72 | HSD17B10 (0.59) | HSD17B10USP2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18769149 | 0.72 | HSD17B10 (0.67) | HSD17B10ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL23498488 | 0.70 | HSD17B10 (0.50) | HSD17B10ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9403764 | 0.68 | HSD17B10 (0.61) | HSD17B10ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL14694017 | 0.68 | ALDH1A1 (0.66) | HSD17B10ALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL24575916 | 0.68 | EPHX2 (0.83) | HSD17B10ALDH1A1HPGDRAB9AKMT2A | |
| SCHEMBL18415483 | 0.68 | POLB (0.77) | HSD17B10ALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL23498689 | 0.68 | HSD17B10 (0.47) | HSD17B10USP2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14470482 | 0.68 | HSD17B10 (0.72) | HSD17B10USP2ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114038-B1 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES | BAYER CROPSCIENCE AG (DE) | 2003-12-03 | — | — | EP | disclosed |
| EP-1114038-A1 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES | Bayer Aktiengesellschaft (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015622-A1 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-23 | — | — | WO | disclosed |