SCHEMBL7875786

SCHEMBL7875786

O=C(NCc1ccco1)c1snc(Cl)c1Cl

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 8/20 0.59
ALDH1A1 P00352 7/20 0.59
SMN1; SMN2 Q16637 6/20 0.59
RAB9A P51151 6/20 0.59
MAPT P10636 4/20 0.59
TP53 P04637 1/20 0.59
LMNA P02545 1/20 0.56
NPSR1 Q6W5P4 2/20 0.56
NPC1 O15118 5/20 0.55
KDM4E B2RXH2 1/20 0.55
MAPK1 P28482 1/20 0.55
TSHR P16473 2/20 0.54
KMT2A Q03164 2/20 0.54
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
POLB P06746 1/20 0.52
HTT P42858 1/20 0.51
HSD17B10 Q99714 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6970815 0.80 HSD17B10 (0.56) HPGDALDH1A1SMN1; SMN2RAB9AMAPT
SCHEMBL7978455 0.73 TP53 (0.51) ALDH1A1SMN1; SMN2RAB9AMAPTTP53
SCHEMBL14338388 0.72 POLB (0.60) HPGDALDH1A1SMN1; SMN2RAB9AMAPT
SCHEMBL7084526 0.72 ALDH1A1 (0.34) HPGDALDH1A1SMN1; SMN2KDM4EMAPK1
SCHEMBL2422719 0.72 TDP1 (0.73) HPGDALDH1A1SMN1; SMN2RAB9AMAPT
SCHEMBL6358692 0.71 HPGD (0.66) HPGDALDH1A1SMN1; SMN2RAB9AMAPT
SCHEMBL11396252 0.71 ALDH1A1 (0.56) HPGDALDH1A1SMN1; SMN2RAB9AMAPT
SCHEMBL15626289 0.71 ALDH1A1 (0.56) HPGDALDH1A1SMN1; SMN2RAB9AMAPT
SCHEMBL10805444 0.71 ALDH1A1 (0.63) HPGDALDH1A1SMN1; SMN2RAB9AMAPT
SCHEMBL30639190 0.71 HPGD (0.69) HPGDALDH1A1SMN1; SMN2MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310005-B1 FUNGICIDES, PESTICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-10-30 US disclosed