Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 2/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697619 | 0.82 | KMT2A (0.41) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL698190 | 0.80 | KMT2A (0.52) | KMT2AADRA2AADRA1AADRA2CADRA1D | |
| SCHEMBL703857 | 0.80 | KMT2A (0.39) | KMT2ANPC1RAB9AMC4RALDH1A1 | |
| SCHEMBL697273 | 0.78 | KMT2A (0.50) | SMPD3KMT2AADRA2AADRA1AADRA2C | |
| SCHEMBL697771 | 0.76 | SMPD3 (0.42) | SMPD3KMT2AADRA2AADRA1AADRA2C | |
| SCHEMBL698900 | 0.74 | KMT2A (0.46) | KMT2AADRA2AADRA1AADRA2CADRA1D | |
| SCHEMBL696517 | 0.72 | TAAR1 (0.47) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28007494 | 0.72 | KMT2A (0.54) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL697904 | 0.72 | KMT2A (0.42) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3923733 | 0.72 | MC4R (0.46) | SMPD3ADRA2AADRA1AADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |