Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696873 | 0.85 | KMT2A (0.55) | KMT2AADRA2AADRA1AADRA2CADRA1D | |
| SCHEMBL697619 | 0.85 | KMT2A (0.41) | KMT2ATAAR1NPC1RAB9AF2RL1 | |
| SCHEMBL697273 | 0.83 | KMT2A (0.50) | KMT2AADRA2AADRA1AADRA2CADRA1D | |
| SCHEMBL703857 | 0.82 | KMT2A (0.39) | KMT2ATAAR1NPC1RAB9AF2RL1 | |
| SCHEMBL698900 | 0.82 | KMT2A (0.46) | KMT2AADRA2AADRA1AADRA2CADRA1D | |
| SCHEMBL697082 | 0.80 | SMPD3 (0.38) | KMT2AADRA2AADRA1AADRA2CADRA1D | |
| SCHEMBL697291 | 0.78 | KMT2A (0.46) | KMT2ATAAR1NPC1RAB9AGLA | |
| SCHEMBL702086 | 0.77 | KMT2A (0.46) | KMT2AADRA2AADRA1AADRA2CADRA1D | |
| SCHEMBL697561 | 0.76 | KMT2A (0.44) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL696517 | 0.74 | TAAR1 (0.47) | KMT2ATAAR1NPC1RAB9AF2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |