Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697260 | 0.83 | NPC1 (0.50) | SMPD3NPC1RAB9AADRA2AADRA2C | |
| SCHEMBL697082 | 0.76 | SMPD3 (0.38) | SMPD3NPC1RAB9AADRA2AADRA2C | |
| SCHEMBL697814 | 0.75 | RAB9A (0.46) | NPC1RAB9AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL697991 | 0.72 | CYP1A2 (0.41) | SMPD3NPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL697291 | 0.71 | KMT2A (0.46) | NPC1RAB9AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11137294 | 0.70 | NPC1 (0.42) | SMPD3NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL697121 | 0.69 | TYK2 (0.43) | SMPD3NPC1RAB9AADRA2AADRA2C | |
| SCHEMBL1573101 | 0.69 | TYK2 (0.43) | SMPD3NPC1RAB9AADRA2AADRA2C | |
| SCHEMBL697617 | 0.69 | NPC1 (0.42) | SMPD3NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL697619 | 0.69 | KMT2A (0.41) | NPC1RAB9AALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |