Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250144 | 0.86 | SRC (0.52) | MTNR1AMTNR1BSRCPOLBALDH1A1 | |
| SCHEMBL627377 | 0.86 | SRC (0.52) | MTNR1AMTNR1BSRCPOLBALDH1A1 | |
| SCHEMBL5744468 | 0.86 | TACR3 (0.48) | MTNR1AMTNR1BSRCPOLBHSD17B10 | |
| SCHEMBL890060 | 0.86 | TACR3 (0.48) | MTNR1AMTNR1BSRCPOLBHSD17B10 | |
| SCHEMBL3376625 | 0.86 | SRC (0.52) | MTNR1AMTNR1BSRCPOLBALDH1A1 | |
| SCHEMBL18610229 | 0.86 | TACR3 (0.48) | MTNR1AMTNR1BSRCPOLBHSD17B10 | |
| SCHEMBL5936861 | 0.84 | SRC (0.50) | MTNR1AMTNR1BSRCALDH1A1KMT2A | |
| SCHEMBL19658438 | 0.82 | LMNA (0.46) | MTNR1AMTNR1BSRCPOLB | |
| SCHEMBL10650407 | 0.82 | MTNR1A (0.44) | MTNR1AMTNR1BSRCPOLBHSD17B10 | |
| SCHEMBL22361550 | 0.82 | MTNR1A (0.44) | MTNR1AMTNR1BSRCPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |