Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970851 | 1.00 | CCR5 (0.56) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6973106 | 0.94 | OPRK1 (0.53) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6973107 | 0.94 | OPRK1 (0.53) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6973690 | 0.90 | OPRK1 (0.56) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6973689 | 0.90 | OPRK1 (0.56) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6983486 | 0.90 | CCR5 (0.58) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8642848 | 0.90 | CCR5 (0.58) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6983483 | 0.90 | CCR5 (0.58) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6979616 | 0.90 | OPRK1 (0.55) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6979619 | 0.90 | OPRK1 (0.55) | OPRK1OPRM1OPRD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-B1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6110947-A | AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |
| US-5952369-A | ANALGESIC, TREATMENT FOR STROKE OR ABDOMINAL PAIN ASSOCIATED WITH FUNCTIONAL BOWEL DISEASE | PFIZER INC (US) | 1999-09-14 | — | — | US | disclosed |
| WO-1996030339-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1996-10-03 | — | — | WO | disclosed |