SCHEMBL6970916

SCHEMBL6970916

CCC[Si]([O])(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
PSIP1 O75475 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
NAAA Q02083 1/20 0.32
LMNA P02545 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
KCNA5 P22460 1/20 0.32
SHMT2 P34897 1/20 0.32
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599107 0.86 NAAA (0.38) CES2CES1ALDH1A1SMN1; SMN2NAAA
SCHEMBL6963558 0.85 NAAA (0.41) CES2CES1ALDH1A1HPGDNAAA
SCHEMBL6960166 0.83 NAAA (0.43) CES2CES1ALDH1A1NAAAHTT
SCHEMBL6957948 0.81 NAAA (0.36) TP53PSIP1CES2CES1KDM4E
SCHEMBL3971800 0.80 MAPT (0.39) TP53PSIP1CES2CES1KDM4E
SCHEMBL9334594 0.79 MAPT (0.36) TP53PSIP1CES2CES1KDM4E
SCHEMBL10730048 0.75 ESR1 (0.45) TP53PSIP1CES2CES1KDM4E
SCHEMBL3889886 0.75 NR1H2 (0.50) TP53PSIP1CES2CES1KDM4E
SCHEMBL28218923 0.75 TP53 (0.38) TP53PSIP1KDM4EALDH1A1GAA
SCHEMBL13089067 0.73 ESR1 (0.38) TP53PSIP1KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291031-B Polymetaloxane, method for producing same, composition thereof, cured film, method for producing same, member provided with same, and electronic component 东丽株式会社 2021-06-15 CN claimed
US-20240132675-A1 POLYMER HAVING METAL-OXYGEN-METAL BOND AS PRIMARY CHAIN, COMPOSITION THEREOF, SOLID MATERIAL AND PRODUCTION METHOD THEREOF, AND ELECTRONIC COMPONENT AND FIBER TORAY INDUSTRIES, INC. (JP) 2024-04-25 US disclosed
US-20240002607-A1 POLYMETALLOXANE, COMPOSITION OF SAME, CURED FILM, METHOD OF PRODUCING THE CURED FILM, MEMBER AND ELECTRONIC COMPONENT EACH PROVIDED WITH THE CURED FILM, FIBER, AND METHOD OF PRODUCING THE FIBER TORAY INDUSTRIES, INC. (JP) 2024-01-04 US disclosed
US-11795064-B2 Polymetalloxane, method for producing same, composition thereof, cured film and method for producing same, and members and electronic components provided with same TORAY INDUSTRIES, INC. (JP) 2023-10-24 US disclosed
US-20230331927-A1 POLYMETALLOXANE-CONTAINING COMPOSITION, CURED BODY, MEMBER, ELECTRONIC COMPONENT, AND FIBER TORAY INDUSTRIES, INC. (JP) 2023-10-19 US disclosed
EP-3689891-B1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-03-01 EP disclosed
CN-108291031-B Polymetaloxane, method for producing same, composition thereof, cured film, method for producing same, member provided with same, and electronic component 东丽株式会社 2021-06-15 CN disclosed
US-20210108339-A1 METHOD FOR PRODUCING METAL OXIDE FIBERS, AND METAL OXIDE FIBERS TORAY INDUSTRIES, INC. (JP) 2021-04-15 US disclosed
EP-3779001-A1 METHOD FOR PRODUCING METAL OXIDE FIBERS, AND METAL OXIDE FIBERS Toray Industries, Inc. (JP) 2021-02-17 EP disclosed
CN-111971425-A Method for producing metal oxide fiber and metal oxide fiber 东丽株式会社 2020-11-20 CN disclosed
US-20200247957-A1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-08-06 US disclosed
EP-3689891-A1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION Kyushu University, National University Corporation (JP) 2020-08-05 EP disclosed
EP-3381969-B1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME TORAY INDUSTRIES (JP) 2020-06-03 EP disclosed
CN-111132990-A Cobalt complex, process for producing the same, and catalyst for hydrosilylation 国立大学法人九州大学 2020-05-08 CN disclosed
US-20180327275-A1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME TORAY INDUSTRIES, INC. (JP) 2018-11-15 US disclosed
EP-3381969-A1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME Toray Industries, Inc. (JP) 2018-10-03 EP disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200247957-A1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION OR51E2, WEE2, SLC39A11 TP53 2972/4885PSIP1 36/4885CES2 824/4885
US-11795064-B2 Polymetalloxane, method for producing same, composition thereof, cured film and method for producing same, and members and electronic components provided with same ASH2L, SETDB1, BMI1 TP53 2420/4885PSIP1 1334/4885CES2 3090/4885
US-20180327275-A1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME ASH2L, SETDB1, BMI1 TP53 2420/4885PSIP1 1334/4885CES2 3090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.