SCHEMBL6957948

SCHEMBL6957948

CCC[Si]([O])(CCC)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.36
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 1/20 0.35
KCNA5 P22460 3/20 0.35
TP53 P04637 1/20 0.35
PSIP1 O75475 1/20 0.34
KMT2A Q03164 1/20 0.34
EPHX1 P07099 3/20 0.34
ALDH1A1 P00352 1/20 0.34
KCNN4 O15554 2/20 0.33
KDM4E B2RXH2 1/20 0.33
RAB9A P51151 1/20 0.33
EPHX2 P34913 1/20 0.33
PKM P14618 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6963975 0.86 SMN1; SMN2 (0.41) NAAAHTTSMN1; SMN2TSHREPHX1
SCHEMBL6965425 0.85 EPHX2 (0.42) NAAAHTTSMN1; SMN2EPHX1ALDH1A1
SCHEMBL6972289 0.83 EPHX2 (0.44) NAAAHTTSMN1; SMN2EPHX1ALDH1A1
SCHEMBL6970916 0.81 TP53 (0.35) NAAAHTTSMN1; SMN2TSHRKCNA5
SCHEMBL2483998 0.80 TP53 (0.38) SMN1; SMN2TSHRTP53PSIP1ALDH1A1
SCHEMBL9334594 0.79 MAPT (0.36) NAAASMN1; SMN2KCNA5TP53PSIP1
SCHEMBL3889886 0.75 NR1H2 (0.50) NAAATSHRKCNA5TP53PSIP1
SCHEMBL10730048 0.75 ESR1 (0.45) TSHRTP53PSIP1KMT2AALDH1A1
SCHEMBL28218923 0.75 TP53 (0.38) TSHRTP53PSIP1KMT2AALDH1A1
SCHEMBL13089067 0.73 ESR1 (0.38) SMN1; SMN2TSHRKCNA5TP53PSIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240132675-A1 POLYMER HAVING METAL-OXYGEN-METAL BOND AS PRIMARY CHAIN, COMPOSITION THEREOF, SOLID MATERIAL AND PRODUCTION METHOD THEREOF, AND ELECTRONIC COMPONENT AND FIBER TORAY INDUSTRIES, INC. (JP) 2024-04-25 US disclosed
US-20240002607-A1 POLYMETALLOXANE, COMPOSITION OF SAME, CURED FILM, METHOD OF PRODUCING THE CURED FILM, MEMBER AND ELECTRONIC COMPONENT EACH PROVIDED WITH THE CURED FILM, FIBER, AND METHOD OF PRODUCING THE FIBER TORAY INDUSTRIES, INC. (JP) 2024-01-04 US disclosed
US-11795064-B2 Polymetalloxane, method for producing same, composition thereof, cured film and method for producing same, and members and electronic components provided with same TORAY INDUSTRIES, INC. (JP) 2023-10-24 US disclosed
US-20230331927-A1 POLYMETALLOXANE-CONTAINING COMPOSITION, CURED BODY, MEMBER, ELECTRONIC COMPONENT, AND FIBER TORAY INDUSTRIES, INC. (JP) 2023-10-19 US disclosed
WO-2022202398-A1 POLYMER HAVING METAL-OXYGEN-METAL BOND AS PRIMARY CHAIN, COMPOSITION THEREOF, SOLID MATERIAL AND PRODUCTION METHOD THEREOF, AND ELECTRONIC COMPONENT AND FIBER 東レ株式会社 2022-09-29 WO disclosed
US-20210108339-A1 METHOD FOR PRODUCING METAL OXIDE FIBERS, AND METAL OXIDE FIBERS TORAY INDUSTRIES, INC. (JP) 2021-04-15 US disclosed
EP-3779001-A1 METHOD FOR PRODUCING METAL OXIDE FIBERS, AND METAL OXIDE FIBERS Toray Industries, Inc. (JP) 2021-02-17 EP disclosed
EP-3381969-B1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME TORAY INDUSTRIES (JP) 2020-06-03 EP disclosed
US-20180327275-A1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME TORAY INDUSTRIES, INC. (JP) 2018-11-15 US disclosed
EP-3381969-A1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME Toray Industries, Inc. (JP) 2018-10-03 EP disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795064-B2 Polymetalloxane, method for producing same, composition thereof, cured film and method for producing same, and members and electronic components provided with same ASH2L, SETDB1, BMI1 NAAA 2989/4885HTT 4522/4885SMN1; SMN2 1535/4885
US-20180327275-A1 POLYMETALLOXANE, METHOD FOR PRODUCING SAME, COMPOSITION THEREOF, CURED FILM AND METHOD FOR PRODUCING SAME, AND MEMBERS AND ELECTRONIC COMPONENTS PROVIDED WITH SAME ASH2L, SETDB1, BMI1 NAAA 2989/4885HTT 4522/4885SMN1; SMN2 1535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.