Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504041 | 0.94 | KMO (0.46) | KMOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1027569 | 0.82 | NOS1 (0.49) | KMOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6963040 | 0.81 | KMO (0.64) | KMOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25260021 | 0.81 | KMO (0.46) | KMOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2549381 | 0.79 | KMO (0.59) | KMOLMNACYP1A2TSHRBLM | |
| SCHEMBL30770947 | 0.78 | KMO (0.44) | KMOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30483748 | 0.77 | KMO (0.46) | KMOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4812924 | 0.77 | KMO (0.46) | KMOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25289763 | 0.77 | KMO (0.46) | KMOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5539451 | 0.76 | NOS1 (0.53) | KMOLMNACYP1A2TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855391-B1 | NOVEL ISOQUINOLINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| EP-1316550-A1 | 6-Acylamino-5-substituted-benzoxazol-2-one compounds and method for using them | EASTMAN KODAK COMPANY (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6515176-B1 | Disclosed is a 6-acylamino-5-substituted-benzoxazol-2-one compound having the structural formula I: Also disclosed is a method for forming a cyan dye-forming coupler from the above compound. The method and intermediate with a simplified | EASTMAN KODAK COMPANY | 2003-02-04 | — | — | US | disclosed |
| US-5959107-A | Isoquinoline derivatives | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0855391-A1 | NOVEL ISOQUINOLINE DERIVATIVES | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| EP-0385664-B1 | Antiinflammatory benzoxazolones | PFIZER (US) | 1994-01-12 | — | — | EP | disclosed |
| US-5149821-A | Process and intermediates for optically active 3-formyltetrahydropyrans | PFIZER INC (US) | 1992-09-22 | — | — | US | disclosed |
| US-5086062-A | Inhibitors of lipoxygenase and-or cyclooxygenase enzymes | PFIZER INC. (US) | 1992-02-04 | — | — | US | disclosed |
| EP-0385664-A2 | Antiinflammatory benzoxazolones | PFIZER INC. (US) | 1990-09-05 | — | — | EP | disclosed |