Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | SCD | O00767 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69157 | 0.83 | MAPT (0.72) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL71299 | 0.80 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL768649 | 0.80 | ACR (0.63) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL892678 | 0.77 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL17789551 | 0.77 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL18619869 | 0.77 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL16373714 | 0.77 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2678323 | 0.77 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6710446 | 0.77 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL10545373 | 0.77 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |