Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 8/20 | 0.45 |
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.45 |
| ▸ | RARG | P13631 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321708 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MEN1MAPTKMT2AOPRK1 | |
| SCHEMBL12844164 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MEN1MAPTKMT2AOPRK1 | |
| SCHEMBL14736417 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MEN1MAPTKMT2AOPRK1 | |
| SCHEMBL12775968 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MEN1MAPTKMT2AOPRK1 | |
| Hydrochloric Acid SCHEMBL14736655 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTKMT2AOPRK1 | |
| SCHEMBL2226979 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTKMT2AOPRK1 | |
| SCHEMBL9229324 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MEN1MAPTKMT2AOPRK1 | |
| SCHEMBL14736416 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1MAPTKMT2AOPRK1 | |
| Hydrochloric Acid SCHEMBL7490273 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MEN1MAPTKMT2AOPRK1 | |
| SCHEMBL6810806 | 0.76 | AR (0.51) | ALDH1A1MEN1MAPTKMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629624-B1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0643050-B1 | Oxazolidinedione derivatives and their use as hypoglycemic agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-04-10 | — | — | EP | disclosed |
| CN-1068326-C | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | CN | disclosed |
| US-5614544-A | HYPOGLYCEMIC AND HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5591862-A | ANTILIPEMICS, TREATING DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| CN-1124246-A | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-06-12 | — | — | CN | disclosed |
| EP-0643050-A1 | Oxazolidinedione derivatives and their use as hypoglycemic agent | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |